---
title: NanoCuvette™ S - cphnano.com
description: Affordable upgrade for your existing UV-Vis spectrophotometer. The NanoCuvette™ is an excellent improvement in workflow for quantitative analysis.
image: https://cphnano.com/hubfs/PHOS_20181221_nanocuvette_being_held_small.png
---

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# NanoCuvette™ S

 

#### Particle Size Analysis Using UV-Vis Spectrophotometer

## Next-gen Scattering Analysis

The NanoCuvette™ S allows for spectrophotometric quantification of particle/cell size and concentration analysis in numerous industries such as biotechnology, pharmaceuticals, life science, foods, including various industrial applications for quality control.

The capacity of NanoCuvette™ S goes far beyond any product currently on the market in terms of achieving easy, fast, and reliable particle/cell size analysis and concentration determination. With the NanoCuvette™ S you have the functionality to determine small particles down to 50 nm, while simultaneously quantify their concentration.

 

[Product Brief](https://cphnano.com/hubfs/INDS_20220106_Nanocuvette_S_Product_brief.pdf)

[Application Notes](https://knowledge.cphnano.com/en/pages/nanocuvette-s#application-notes)

[![BLEN_20210812_nanocuvette_s_microcuvette_resized_800 x 1264](https://cphnano.com/hs-fs/hubfs/BLEN_20210812_nanocuvette_s_microcuvette_resized_800%20x%201264.png?width=340&height=537&name=BLEN_20210812_nanocuvette_s_microcuvette_resized_800%20x%201264.png "BLEN_20210812_nanocuvette_s_microcuvette_resized_800 x 1264")](https://knowledge.cphnano.com/en/pages/nanocuvette-one-data-sheet)

## Expanding Capabilities

The NanoCuvette™ S expands the capabilities of your spectrophotometer and allows you to perform combined angle-resolved light scattering and absorbance at 190-1100 nm. Integrated in the surface is a patented photonic nanocrystal (optical filter), that register light scattering such that it measures particle sizes near the photonic crystal surface.

![PHOT_20221014_nanocuvette_s_product_shots_5_resized_2200x1467](https://cphnano.com/hs-fs/hubfs/PHOT_20221014_nanocuvette_s_product_shots_5_resized_2200x1467.jpeg?width=2560&height=1707&name=PHOT_20221014_nanocuvette_s_product_shots_5_resized_2200x1467.jpeg "PHOT_20221014_nanocuvette_s_product_shots_5_resized_2200x1467")

## Why Upgrade to NanoCuvette™ S 

Traditionally, spectrophotometry laboratory work has been limited by lack of robust methods to determine size and concentrations. We upgrade UV-Vis spectrophotometry around the world and across all major instrument brands to create new ways to determine particle size analysis, perfom refractive index measurements in a label-free, fast, cheap, and reliable method.

## Technology: How we do it

### Absorption versus label-free spectroscopy

With absorption spectroscopy, the [Beer–Lambert law](https://knowledge.cphnano.com/en/pages/what-is-the-beer-lambert-law) relates the attenuation of light to the properties of the material through which the light is traveling:

A = εcl + A0 ,

![ILLU_20160313_NanoCuvette_Principle_Simple_Abs_275x150](https://cphnano.com/hubfs/ILLU_20160313_NanoCuvette_Principle_Simple_Abs_275x150.png "ILLU_20160313_NanoCuvette_Principle_Simple_Abs_275x150")

where A is the absorbance, ε is molar extinction coefficient, c is the concentration, l is the path length and A0 is the background absorbance.

Lambert, J.H. (1760). Photometria sive de mensura et gradibus luminis, colorum et umbrae \[Photometry, or, On the measure and gradations of light intensity, colors, and shade\] (in Latin). Augsburg, (Germany): Eberhardt Klett.

Beer (1852). "Bestimmung der Absorption des rothen Lichts in farbigen Flüssigkeiten" \[Determination of the absorption of red light in colored liquids\]. Annalen der Physik und Chemie (in German). 162 (5): 78–88. Bibcode:1852AnP...162...78B. doi:10.1002/andp.1852162050

In contrast, when light hits a nanoscale photonic crystal, the resonance wavelength is related to the refractive index or concentration close to the surface:

λ = β(αc + ns) + λ0 ,

![ILLU_20160313_NanoCuvette_Principle_Simple_275x150](https://cphnano.com/hubfs/ILLU_20160313_NanoCuvette_Principle_Simple_275x150.png "ILLU_20160313_NanoCuvette_Principle_Simple_275x150")

where λ is the wavelength, β is a coefficient, α is the specific refractive increment, c is the concentration, ns is the solvent refractive index and λ0 is the reference resonance wavelength. This is called label-free spectroscopy

Nano Lett. 2014, 14, 8, 4499–4504Publication Date:July 8, 2014https://doi.org/10.1021/nl5014986Copyright © 2014 American Chemical Society.

Højlund-Nielsen, E., Clausen, J., Mäkela, T., Thamdrup, L. H., Zalkovskij, M., Nielsen, T., Pira, N. L., Ahopelto, J., Mortensen, N. A., Kristensen, A. (2016). Plasmonic Colors: Toward Mass Production of Metasurfaces. Adv. Mater. Technol., 1: 1600054. doi: 10.1002/admt.201600054

#### Particle Sizing and Concentrations in the Palm of Your Hand.

## Key Uses

![DSC03249-1](https://cphnano.com/hubfs/DSC03249-1.jpeg "DSC03249-1")

- #### Label-free measurements at different volumes (100 - 200 μL)
- #### Size analysis of particles from 50 nm to 3000 nm with concentration detection limit of 0,0001% to 0,1%
- #### Surface refractive index range measurements at 1.0 - 1.6 nD
- #### Turbidity and impurity QC- measurements

# Want NanoCuvette™ S or a Demo? 

 

[Book Online meeting](https://nanocuvette.cphnano.com/meetings/emiho)

#### Lab Work Has Never Been Easier

### User Centric Experience

With NanoCuvette™ S particles can be quantified in minutes with enhanced sensitivity, reliability, and reproducibility. It measures concentrations and sizes in a standard spectrophotometer without expensive specialized instrument. Together with the unique user-centric online software SpectroWorks™ it automatically analyses the results in minutes. 

Furthermore, NanoCuvette™ S have the free ”Basic cuvette” spectrum file functionality in SpectroWorks™, which you can use for automatic standard curve processing by using our free report template in our Colab Notebook.

![PHOS_20210805_nanocuvette_s_microcuvette_photoshoot_03_resized_1500x2377](https://cphnano.com/hubfs/PHOS_20210805_nanocuvette_s_microcuvette_photoshoot_03_resized_1500x2377.jpg "PHOS_20210805_nanocuvette_s_microcuvette_photoshoot_03_resized_1500x2377")

## Static Light Scattering and Cloud Computing

Particle can be measured since light scattering depends on angle and wavelength. NanoCuvette™ S utilizes Rayleigh and Mie scattering at any given time to precisely determine the sizes in the dispersion of both large and small particles. SpectroWorks™ use the scattered light to model the size and concentration within the sample using more than 500 million light simulations.

![ILLU_20211104_Laptop_Display_SpectroWorks_2084×1251px](https://cphnano.com/hubfs/ILLU_20211104_Laptop_Display_SpectroWorks_2084%C3%971251px.png "ILLU_20211104_Laptop_Display_SpectroWorks_2084×1251px")

#### Superior technology with no Up-front Cost or Training for Your Lab

## Key Features

![EXTF_20210413_Font_Awesome_box_check_Red](https://cphnano.com/hubfs/EXTF_20210413_Font_Awesome_box_check_Red.svg "EXTF_20210413_Font_Awesome_box_check_Red")

##### SUPPORTS MAJOR BRANDS

Improved and affordable upgrade for your existing UV-Vis spectrophotometer. Also allows basic cuvette measurements.

![EXTF_20210413_Font_Awesome_users_Red](https://cphnano.com/hubfs/EXTF_20210413_Font_Awesome_users_Red.svg "EXTF_20210413_Font_Awesome_users_Red")

##### DESIGNED FOR HUMANS

Easy to use with no special training required. [Online support included](https://knowledge.cphnano.com/en/pages/support-for-nanocuvette-one).

![EXTF_20210413_Font_Awesome_chart_line_Red](https://cphnano.com/hubfs/EXTF_20210413_Font_Awesome_chart_line_Red.svg "EXTF_20210413_Font_Awesome_chart_line_Red")

##### ACCURATE AND INSTANT RESULTS

Results are calculated based on spectral analysis. Our engine in [SpectroWorks™](https://knowledge.cphnano.com/en/pages/what-is-spectroworks) is fast and makes it a breeze to extract results. 

![EXTF_20210413_Font_Awesome_id_card_red](https://cphnano.com/hubfs/EXTF_20210413_Font_Awesome_id_card_red.svg "EXTF_20210413_Font_Awesome_id_card_red")

##### UNIQUE TRACEABILITY

Made in Denmark with unique ID for traceability and access to online calibration data.

![EXTF_20220930_Font_Awesome_recycle-solid](https://cphnano.com/hs-fs/hubfs/EXTF_20220930_Font_Awesome_recycle-solid.png?width=68&height=60&name=EXTF_20220930_Font_Awesome_recycle-solid.png "EXTF_20220930_Font_Awesome_recycle-solid")

##### SEMI-REUSABLE CUVETTES

The NanoCuvettes™ can be re-used up to a certain amount [depending on application and maintenance](https://knowledge.cphnano.com/en/pages/nanoucuvette-one-cleaning-manual).

![EXTF_20210413_Font_Awesome_vial_red](https://cphnano.com/hubfs/EXTF_20210413_Font_Awesome_vial_red.svg "EXTF_20210413_Font_Awesome_vial_red")

##### LESS SAMPLE NEEDED FOR ANALYSIS

 Measurements at different volumes between 100 - 200μL

#### Upgrade Your UV-Vis Spectrophotometer to do Particle Size and Concentration Analysis.

## Ready to try NanoCuvette™ S ?

![PHOT_20221014_nanocuvette_s_product_shots_6_resized_2200x1467](https://cphnano.com/hs-fs/hubfs/PHOT_20221014_nanocuvette_s_product_shots_6_resized_2200x1467.jpeg?width=900&height=600&name=PHOT_20221014_nanocuvette_s_product_shots_6_resized_2200x1467.jpeg "PHOT_20221014_nanocuvette_s_product_shots_6_resized_2200x1467")

 

*\*Purchasing NanoCuvette™ S at reseller includes life-time access, data storage and upgrades to SpectroWorks™, free support and  individual calibration for best performance. Price per measurement may vary depending on sample and use.*

![PHOT_20210505_vwr_webinar_photoshoot_02_square_resized_1600x1600](https://cphnano.com/hs-fs/hubfs/PHOT_20210505_vwr_webinar_photoshoot_02_square_resized_1600x1600.jpg?width=1600&height=1600&name=PHOT_20210505_vwr_webinar_photoshoot_02_square_resized_1600x1600.jpg "PHOT_20210505_vwr_webinar_photoshoot_02_square_resized_1600x1600")

#### Your Expert in UV-Vis Technology

## Need help getting started? We have got you covered.

[Book Online meeting](https://nanocuvette.cphnano.com/meetings/emiho)

# Want to Learn More?

### Contact us for more information on your specific instrument.

![AFDE_20250411_Copenhagen_Nanosystems_Logo_White](https://cphnano.com/hubfs/Logos/AFDE_20250411_Copenhagen_Nanosystems_Logo_White.svg "AFDE_20250411_Copenhagen_Nanosystems_Logo_White")

Next-Generation Spectroscopy. We empower forward-thinking organisations by delivering innovative and affordable lab and on-site solutions. We make liquid analysis accessible and easy to use.

Winner of *KPMG Global Tech Innovator Award 2022* in Denmark.

Copenhagen Nanosystems A/S  
(cphnano A/S)   
Agern Alle 3,   
DK-2970 Hørsholm,  
Denmark  
CVR/VAT: DK-37293903

Bank Account no.: 3409 11794742  
IBAN: DK1430000011794742  
SWIFT: DABADKKK

#### Shop and Learn

- [NanoCuvette™ One](https://cphnano.com/en/nanocuvette-one)
- [NanoCuvette™ S](https://cphnano.com/nanocuvette-s)
- [SpectroLink™](https://cphnano.com/en/spectrolink)
- [SpectroWorks™](https://cphnano.com/spectroworks)

#### Resources

- [UV-Vis Database](https://knowledge.cphnano.com/en/pages/uv-vis-spectrophotometers)
- [Knowledge Base](https://knowledge.cphnano.com/en/pages)
- [Resellers](https://cphnano.com/en/resellers)

#### About cphnano

- [Contact cphnano](https://cphnano.com/en/contact-us)
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